Anton Paar has launched a new generation of inline refractometers.

The new models L-Rix 5000, L-Rix 5100 and L-Rix 5200 maintain the selling propositions of their predecessors, while adding flexibility, modularity, ease-of-use and data communication options of the new Pico 3000 transmitter.

Measuring with an accuracy of up to ± 0,05°Brix and a repeatability of up to ± 0,025°Brix, the inline refractometers are suited for beverage, food, pulp & paper, sugar, dairy, polymer, metal machining, and many other industries.

The leading optics combined with a long-life LED keeps the unit maintenance free for more than 100,000 hours. The EHEDG-certified refractometers are suitable for hygienic applications and ready for cleaning and sterilisation in place at temperatures up to 145°C. 

The new PN3621 Multi-Angle Light Scattering (MALS) detector from Postnova Analytics combines excellent performance, high precision and reliability to facilitate advanced characterisation of proteins, conjugates, macromolecules and nanoparticles.

It is commonly used in conjunction with Gel Permeation Chromatography (GPC-MALS), Size Exclusion Chromatography (SEC-MALS) or Field-Flow Fractionation (FFF-MALS) to determine distributions of mass, size and composition independent of column calibration by reference standards.

Designed for many years of reliable, trouble-free operation the customer-friendly PN3621 incorporates a vertical 'clean by design' flow cell. Unlike MALS instruments with problem prone horizontal flow cells, the vertical cell design 'self-cleans' and also enables large and potentially fragile high molar mass macromolecules to pass through unaltered.

Incorporating a wide range of working angles (7°-164°) the PN3621 MALS ensures high precision in molecular weight and molecular or particle size determination. Employing 21 angles of light scattering detection enables the PN3621 to achieve better results, especially with complex or high molar mass polymers, particles and protein aggregates. Angles below 35° are crucial for precise molar mass and size determination. For this application the system offers a complete set of stable and sensitive low angle detectors at 7°, 12°, 20° and 28°. This outstanding low angle light scattering capability, coupled with high sensitivity, results in high data quality in all applications.

The system comes with highly intuitive, yet powerful software enabling comprehensive analysis of and reporting on light scattering results. It is very compact and lightweight saving valuable laboratory space and enabling you to easily transport and use the detector in different locations.

Asynt has introduced the Multicell Plus - a high-pressure parallel reactor system with a wide choice of configurations for optimised screening of chemical reactions.

Constructed as standard from durable 316 stainless steel - the Multicell Plus is an affordable, compact device that, depending on the configuration chosen, can be used to screen 4, 6, 8 or 10 parallel reactions. A choice of cell size allows the user to perform reactions in parallel with volumes ranging from 30 to 100ml, at pressures of up to 100 bar and temperatures of 300°C. It can be used simply with a hotplate stirrer, for heating only, or can be upgraded to allow for individual heating of every reactor cell. For applications requiring sub-ambient temperatures the Multicell Plus can be supplied with connections for an external circulator.

The key feature of the new solution is that, despite the small footprint, each reactor cell is supplied with multiple inlet/outlet ports to allow for individual optimisation of the reactor configuration. 

There are a wide variety of options available to customise the system including, but not limited to, multi zone heating, individual overhead stirrer drives, cell charging and sampling apparatus, as well as cell-to-cell isolation to allow for differing chemistries and reaction conditions to be employed without the risk of cross-contamination. Asynt can also supply the high-pressure parallel reactor from alternative materials including Hastelloy, Inconel, Titanium and alloy steels, allowing for greater heat capacity and use with particularly corrosive or caustic chemicals.

Each reactor is extremely easy to set-up and use, with a simple and innovative tool-free closure mechanism.  All Asynt high pressure reactors conform to a wide range of national and international safety standards, including the Pressure Equipment Directive 97/23/EC (PED), Pressure Systems Safety Regulations 2000 (PSSR) and British Compressed Gases CP4 Rev2 (1998).

GEA has supplemented its Hilge Hygia range with a 45kw motor, thereby expanding the hygienic pump's performance spectrum to a flow rate of 180 cubic metres per hour. The new version is also suitable for demanding pharmaceutical applications, particularly because the use of high-quality, no-cast materials in CIP- and SIP-capable special pumps is a critical factor in the production of life science products. 

The new product is an end-suction centrifugal pump from the Hygia premium line, which has a proven track record in sterile applications thanks to its electropolished surfaces, high-quality sealing materials and flexible designs. "Our successful pump packs more horsepower under the hood," says Martin Zickler, product manager for hygienic pumps at GEA. "The 45kw allows us to deliver 60% more flow rate than before. Instead of 110 cubic metres per hour, the pump now delivers 180 ­-a quantum leap that enormously increases the performance range of the hygienic pump."
 
Simplified spare parts handling
The remarkable thing is that GEA covers the performance range with just two sizes. "Our customers are used to achieving this performance range with several different sizes. In practical terms, this means that they require numerous mechanical seals and different O-ring sets for operation. Managing such a spare parts inventory requires considerable logistical effort from customers. We can now reduce that considerably," says Zickler. Along with the pharmaceutical industry¹s demands for hygiene, investment and operating costs for process technology are also on the rise. According to Zickler, maintenance and spare parts replacement are also significant cost factors in this sector.
 
The Hygia has a long-standing reputation as a hygienic pump for food and beverage processing. However, GEA sees great potential in pharmaceutical manufacturing, particularly due to critical fluid characteristics such as lack of lubricating properties and the stringent regulations that make pump designs more challenging. "The main applications are, for example, WFI distribution systems (WFI = water for injection)," explains Zickler. In addition to its high-performance pumps, GEA also delivers smooth and cavity-free hygienic design and reliable technical documentation.
 
Non-cast parts that are easy to clean
In order to facilitate cleanability in hygienically sensitive applications, GEA uses forged, deep-drawn and milled components instead of castings for media-contacting parts. "Because of the risk of blowholes, cast parts are particularly undesirable in the pharmaceutical industry. Cleanability would be reduced, thus making it difficult to obtain the 3-A certification," says Zickler. However, both aspects were important parameters for GEA in the development of the pump. All materials have therefore been carefully selected for their use in hygienic processes. The casings are made of forged CrNiMo (1.4404) and have blowhole-free, smooth surfaces. GEA engineers adapted the design of the shaft and impeller ­ which must transfer the now higher forces ­ to match the powerful motor using a high strength CrNiMo 1.4462 duplex steel.

Researchers at TauRx Therapeutics are using the automation capabilities of the Syrris Atlas HD reactor systems to simplify and accelerate process development for their product pipeline.

Based at the company's primary research facilities at the University of Aberdeen, Scotland, the Syrris equipment is an integral part of the quality by design (QBD) process optimisation workflow. Process Chemist Scott Clunas explained: "We have been using the Altas syringe pumps and software for a number of years. This combination of pumps and automation software is very flexible, allowing us to add multiple reagents to a reactor vessel at set intervals, without needing to have somebody at the bench to manually add liquids or swap lines. We have been very happy with the robustness and performance of the pumps, so when we were looking to invest in additional batch reactor systems, Syrris was the logical choice.
 
"We now have four Atlas HD jacketed reactor systems ­- set up as two parallel pairs, each controlled by a single PC ­- allowing us to more quickly and easily perform QBD studies for the production of our active pharmaceutical ingredients. Each of these experiments can run for 24 to 48 hours, so it's essential that we can automate the entire reaction. The Atlas reactor systems ensure that each experiment is performed in exactly the same way every time, eliminating the variability associated with manual processes, giving us a very high degree of process control for consistent results and, ultimately, more robust processes," Scott concluded.
 
 

Jackson ImmunoResearch, manufacturer of secondary antibodies for the life science market, announces a new range of products for scientists developing single-domain VHH antibodies.

The new Anti-Alpaca secondary antibody product line targets the IgG repertoire of camelid immunoglobulins, including whole molecule, subclass and VHH domain specificities. They are raised against alpaca and cross-react with llama.

Anti-Alpaca IgG subclasses 2+3 specific antibodies enable scientists to monitor immune response and pinpoint the optimal B cell harvest timeframe. Anti-Alpaca VHH domain antibodies were also developed to detect single-domain antibodies across all immunotechniques and will be an indispensable tool in diagnostics and drug development.

David A. Fancy PhD, chief operating officer, commented: "Jackson ImmunoResearch is very excited to bring anti-camelid secondary antibodies to the marketplace. The single-domain antibody market is rapidly expanding. These antibodies are 1/10th the size of canonical immunoglobulins making them ideal for drug delivery and super-resolution imaging, among many other potential uses. Secondary antibodies for VHH discovery are designed to support research needs, reduce project time and improve success rates."

With Cleanveyor and Flatveyor, Kabelschlepp Metool offers two innovative systems that were specially designed for cleanrooms with the highest cleanroom classifications. Cables and hoses are guided in flexible, yet robust sheathing. This design is not only particularly lightweight, quiet and space saving, but also ensures little to no abrasion.

“The two cable systems are an ideal supplement to our regular cable carriers,” explains Peter Sebastian Pütz at Kabelschlepp. “They were specially developed for cleanrooms and meet all requirements of this industry.” The Cleanveyor is certified to ISO cleanroom class 1 and therefore the ideal product for use in production and test facilities for semiconductors, LEDs and OLEDs. With a noise level of less than 38 dB(A), this is a particularly quiet solution. Users will also benefit from a long service life of over 10 million cycles. On request, the cable system can be supplied with harnessed cables and pneumatic hoses, which are pre-installed according to customer specifications.

The Flatveyor is a flat cable system as per ISO cleanroom class 2, with internal support elements to allow travel lengths of up to 3m and speeds of up to 2m per second. The support elements act as reliable guides which can be moved in one direction along the intended bending radius, whereby the cables and hoses are guided reliably. For smooth running, the system moves along the minimum bending radius of the cables, whereby a small pitch reduces noise and vibrations during operation. The design was inspired by a flat cable and is particularly space saving and lightweight; the system can easily be integrated into plants. Overall, this solution facilitates reduction of dust and noise generation in cleanrooms and therefore contributes to lowering total costs.

Investigations of 'quantum dots' for looking deeply into body tissues are rapidly evolving, but more work is required to ensure they are safe, according to a new review.

Quantum dots are tiny, nanometre-sized crystals that can be made from a variety of chemical elements and that can emit light in different colors according to their size. Research on their use for looking into the body and 'seeing' tissues, a variety of techniques collectively referred to as biological imaging, has been rapidly evolving since the 1990s. 

Quantum dots that absorb and emit near-infrared light waves are allowing researchers to look deeper into tissues than ever before. This is because infrared light scatters less in the human body than other wavelengths, providing clearer images than conventional fluorescent imaging techniques.

Researchers at Japan's National Institute for Materials Science reviewed the latest studies on near-infrared quantum dots. Studies have shown that they can be used for whole body imaging of animals, or to target specific tissues, such as tumours and lymph nodes.

Quantum dots have been made from a variety of elements and their compounds, including cadmium selenide (CdSe), mercury telluride (HgTe), lead selenide (PbSe), lead sulfide (PbS), indium arsenide (InAs), or simply from silicon (Si) or carbon (C), just to name a few. 

Quantum dots using cadmium and lead are particularly toxic to cells and tissues; these metals also pose a risk to the environment. Some researchers have tried reducing toxicity by using a special non-toxic shell, but these protected quantum dots are not as effective for imaging as non-coated, non-toxic ones based on carbon, silicon or germanium. Silicon quantum dots in particular are promising because they are safe and very efficient at emitting light.

The review team argues that near-infrared quantum dots show promise for biological imaging once safety issues are addressed. More effective methods for their fabrication are also required to obtain higher efficiencies. 

Testa Analytical Solutions reports that its BI-XDC X-Ray Disc Centrifuge is enabling scientists to make accurate, high resolution particle size distribution measurements, from nanometres to tens of micrometres, without time consuming calibration or absorption correction.

Based on the principle of photosedimentation, the BI-XDC measures the size of particles according to the time the particle takes to sediment in the detector according to Stokes law. Combining centrifugal and gravitational sedimentation in a single instrument the BI-XDC sets a new standard for these well-established methods of particle sizing.

Leveraging a highly reliable orthogonal method, the system is proven to give error free quantitative measurements across a broad range of samples including nanoparticles, minerals, clays, ceramics and metal oxides.

Using the sytem there are no optical corrections and no optical properties to worry about, just a simple mass sensitive response based on x-ray absorption. It features a reproducible digitally controlled disk speed to ensure high performance and accuracy. The scanning x-ray head enables measurements to be made typically in just eight minutes.

Thermo Fisher Scientific and Genovis have announced a collaborative research project to develop advanced end-to-end workflows for the preparation, characterisation and monitoring of novel and complex biotherapeutics using liquid chromatography-mass spectrometry (LC-MS).

Bringing together Thermo Fisher's LC-MS technology with the advanced enzyme-based sample preparation and analysis techniques of Genovis will enable the development of robust, automation-ready, magnetic bead and chromatography-based workflows for the streamlined analysis of biotherapeutics. Expertise from Thermo Fisher's Global Customer Solution Centers will also help Genovis to determine optimal hardware/software configurations and suitable consumables for critical quality attribute (CQA) analysis of biotherapeutics during the research and development phase.

"With the shift toward large biological entities, companies are aiming to bring to market medicines with greater affinity and efficacy, but these medicines also present an additional level of analytical complexity," said John Rontree at Thermo Fisher Scientific. "By collaborating with Genovis, we plan to develop comprehensive workflows that provide robust and advanced solutions for preparing and assessing complex biotherapeutics."

"We are excited to work with Thermo Fisher Scientific to continue our goal toward more automated analytical workflows," said Fredrick Olsson, chief executive officer at Genovis. "Through this collaboration we will be able to develop new products and workflows on world-class instrumentation together with experts from Thermo Fisher¹s European Biopharma Customer Solution Center and serve the growing analytical needs of biopharma customers of both companies with meaningful innovations."

The combination of the Thermo Scientific Vanquish Duo UHPLC Systems (with Dual LC workflow) and the Thermo Scientific Chromeleon Chromatography Data System (CDS) Software with the SmartEnzyme technology from Genovis will enable the development of LC-MS-based protocols for O-glycosylation profiling and automated high-throughput workflows for CQA analysis of monoclonal antibodies at the subunit level.

SP Scientific's Genevac EZ-2 Centrifugal Evaporator is providing the Clinical Biochemistry department at a leading UK hospital with a reliable, easy-to-use method of preparing clinical samples ready for testing.

Clinical laboratories play a vital role in the healthcare industry as about 80% of the clinician¹s diagnoses are based on laboratory analysis with a range of tests carried out on clinical specimens, to obtain information about the health of a patient to aid in diagnosis, treatment and prevention of disease. These departments commonly perform automated quantitative tests on serum or plasma patient samples for a wide array of substances including lipids, blood sugar, enzymes and hormones.

The recent introduction of an EZ2 centrifugal evaporation system for clinical biochemistry sample preparation has provided this particular hospital's laboratory staff with considerable advantages compared with the manual dry down evaporation methods previously used.

Using the EZ-2 evaporator the Clinical Biochemistry department has been able to set-up a suite of automated methods whereby the user simply loads samples, selects the appropriate solvent removal method and presses start. Proprietary technology allows the instrument to stop by itself at the end of evaporation process. This frees up staff time to do more productive work than monitoring their evaporator and has increased throughput of the laboratory. Productivity has also been increased as the instrument can handle a large number of samples per run, which are quickly evaporated to dryness in just a matter of minutes.

The enclosed design of the evaporator and cold trap has ensured that waste solvents are collected and staff safety is enhanced as vapours are no longer released into the laboratory atmosphere. 

In addition, the reliability of sample preparation has improved. Not only has the evaporator eliminated cross contamination between samples, but its advanced temperature control avoids sample degradation and hence the need to repeat analyses or doubts about the analytical result obtained. Clinical biochemistry staff say they would find it hard to go back to the old manual methods of evaporative sample preparation used before the EZ-2 arrived. 

AMS Bio has introduced XerumFree, a new concept in cell culture that allows users to culture cells without the use of serum.

XerumFree has been developed taking into account what is missing in traditional basal cell culture media to sustain growth of all cell types, which is a nutritional approach at the cellular level.  

Containing no animal or human derived material, XerumFree is a serum replacement for all cell culture practices that is chemically defined thereby avoiding lot-to-lot variations and eliminating the need for testing new batches of serum. Since it does not contain hormones, cytokines or unknown serum compounds it cannot bias research data. Further as the new solution is animal vesicle free, it is an ideal cell culture medium for exosome research.

XerumFreehas been designed to be easy to use: simply add it to a culture medium as you would do with fetal bovine serum (FBS). Examples of cells that have successfully been cultured on XerumFree enriched medium include Liver epithelial cells, HaCaT, Primary human hepatocytes, Hybridoma, VERO, HEK293, CHO, HEP G2, HeLa and Human keratinocytes

The new PN3621 Multi-Angle Light Scattering (MALS) detector from Postnova Analytics combines excellent performance, high precision and reliability to facilitate advanced characterisation of proteins, conjugates, macromolecules and nanoparticles.

It is commonly used in conjunction with Gel Permeation Chromatography (GPC-MALS), Size Exclusion Chromatography (SEC-MALS) or Field-Flow Fractionation (FFF-MALS) to determine distributions of mass, size and composition independent of column calibration by reference standards.

Designed for many years of reliable, trouble-free operation the customer-friendly PN3621 incorporates a vertical 'clean by design' flow cell. Unlike MALS instruments with problem prone horizontal flow cells, the vertical cell design 'self-cleans' and also enables large and potentially fragile high molar mass macromolecules to pass through unaltered.

Incorporating a wide range of working angles (7°-164°) the PN3621 MALS ensures high precision in molecular weight and molecular or particle size determination. Employing 21 angles of light scattering detection enables the PN3621 to achieve better results, especially with complex or high molar mass polymers, particles and protein aggregates. Angles below 35° are crucial for precise molar mass and size determination. For this application the system offers a complete set of stable and sensitive low angle detectors at 7°, 12°, 20° and 28°. This outstanding low angle light scattering capability, coupled with high sensitivity, results in high data quality in all applications.

The system comes with highly intuitive, yet powerful software enabling comprehensive analysis of and reporting on light scattering results. It is very compact and lightweight saving valuable laboratory space and enabling you to easily transport and use the detector in different locations.

BMG Labtech introduced the new CLARIOstar Plus at the SLAS 2019 meeting. New features including Enhanced Dynamic Range technology, rapid autofocus and dedicated detectors will help users to expand their capabilities in the lab.

The CLARIOstar Plus is a multi-mode microplate reader with advanced LVF Monochromators, highly sensitive filters, and an ultra-fast UV/vis spectrometer. The Enhanced Dynamic Range and automatic focus technologies make manual settings superfluous and detection optimisation easier than ever.

Atmospheric Control Unit, temperature incubation, multiple shaking, well scan and reagent injectors make the CLARIOstar Plus the ideal platform for any live cell-based assay. 

The new Multiplex mode for Zeiss Airyscan 2 delivers more information in less time. Smart illumination and detection schemes allow parallel pixel acquisition for fast and gentle confocal microscopy. Researchers can now image their most challenging three-dimensional samples with high framerates in superresolution. The speed and sensitivity gain can be used to gently capture either fixed samples in larger fields of view with higher throughput and without bleaching, or dynamic processes in living specimens with minimal disturbance.

The Multiplex mode is available for the whole LSM 9 family: LSM 980 is the flexible research platform with complementary multiphoton and superresolution capabilities. LSM 900 is a very compact system that delivers image quality without complexity.
 
The new LSM 980 with Airyscan 2 is the ideal research platform for confocal 4D imaging. The entire beam path is optimized for simultaneous spectral detection of multiple weak labels with the highest light efficiency. Researchers benefit from the full flexibility of a point scanning confocal and the speed and gentleness of the sensitive Airyscan 2 detector. The new Multiplex mode combines an elongated excitation laser spot and parallel pixel readout of this area detector. This allows acquiring up to eight image lines in a single sweep. Users can gently image larger fields of view with superresolution in shorter acquisition times than ever before.

LSM 900 with Airyscan 2 is a very compact confocal microscope for high-end imaging. This system has a small footprint, concentrating on the essence of a confocal and leaving out needless complexity. It fits easily into labs or imaging facilities and is optimised for ease of use. It can be combined with Celldiscoverer 7 for automated confocal imaging with high efficiency.
 
The new Multiplex mode provides more options to fit imaging speeds and resolution to experimental needs. It uses knowledge about the shape of the excitation laser spot and the location of single area detector elements within the Airyscan 2 detector to extract more spatial information ­ even during parallel pixel readout. This allows bigger steps to be taken when sweeping the excitation laser over the field of view, improving achievable acquisition speeds. In fact, the large amount of spatial information captured in the pinhole plane allows the reconstruction of a final image with better resolution than the acquisition sampling.

GiroNEX is showcasing its novel precision powder dispensing technology at the Making Pharmaceuticals event. 

The Making Pharmaceuticals conference is hosting over 2,000 visiting pharma professionals over two days, and 200+ exhibitors from across Europe.

GiroNEX, which announced first details of a novel precision powder dispensing technology at the end of 2018, will be showcasing the Gironex Cube.

The Cube, which combines innovative autonomous technology with a novel robotic dispense system, to make repetitive precision powder dispensing, simple and efficient, aims to significantly increase the pharmaceutical industry's ability to offer patient-specific dosing for more effective treatment of specific conditions.

The new GiroNEX technology can quickly dispense from 0.1 milligrams to 5 grams of pharmaceutical or other chemical powders into vials or capsules and with accuracies of 2% or better across the complete weight range.

This innovative new approach has been specifically developed to target fast-growing opportunities in regulated production environments such as: the use of localised manufacturing to enable pharmaceutical companies to offer more tailored treatments; and by hospital pharmacy compounding units involved in preparing patient- specific doses and drug combinations, nutritional supplements and other materials.

Agilent Technologies has announced a range of new products designed to deliver improved analytical and business outcomes for laboratories involved in a variety of analytical pursuits, including food testing, environmental screening, and metabolomics research.

The centerpiece of the announcement, the new Agilent 6546 quadrupole time-of-flight LC/MS system, gives analysts the ability to acquire high-resolution data across an unprecedented dynamic range. This innovative instrument includes the Q-RAI (Quadrupole-Resolved All Ions), a data-independent acquisition mode which reduces the complexity of MS/MS spectra while maximising the accuracy and quality of the data acquired.

"The Agilent 6546 LC/Q-TOF is a major advancement compared to previous time-of-flight systems because it combines dynamic range with excellent resolution in all conditions (speed, mass range, intensity)," said Nicola Zamboni, head of the Swiss Federal Institute of Technology in Zurich. "In our lab, the 6546 will be a great instrument for challenging applications such as 13C metabolic flux analysis, high-throughput mass spectrometry, and metabolite identification."

MassHunter software complementing the Agilent 6546 LC/Q-TOF includes:

MassHunter Quantitative Analysis 10.0 software with new features that allow labs to more quickly and accurately screen complex sample sets for both target and suspect compounds in a single workflow, ideal for food safety, and environmental analysis.

New MassHunter Classifier software which complements the enhanced method development workflow in the Mass Profiler Professional (MPP) software, enabling faster testing for food authenticity with results that are easier to review.

MassHunter Lipid Annotator that presents theoretical lipid MS/MS annotations for Q-TOF results with support through the MassHunter Mass Profiler Professional Lipidomics workflow.

Agilent also announced the new Agilent Bravo Metabolomics Sample Prep Platform, the perfect partner for the Agilent 6546 LC/Q-TOF‹which provides consistent and accurate preparation of human plasma samples for metabolomics analysis via LC/MS.

"Together, these new products will enable laboratories to spend less time getting the answers they need - and increase the confidence they have in their results," said Monty Benefiel, Agilent vice president, and general manager of the company's Mass Spectrometry Division.

Lonza has announced the global availability of its fully automated and integrated plate-based PyroTec Pro Robotic Solution for endotoxin testing. Combining the speed and reproducibility of a robotic liquid handling platform with the power of version 6.0 of Lonza’s WinKQCL software, the system simplifies and accelerates endotoxin testing of parenteral pharmaceuticals regardless of sample complexity.

“We are committed to developing new technologies to enable a safer and healthier living,” said Allen Burgenson, Global Subject Matter Expert for Testing Services at Lonza. “In line with this vision, our new PyroTec Pro Robotic Platform offers quick time-to-result to expedite the delivery of safe medicines to improve patient healthcare. Scientists at QC testing laboratories can feel confident that the generated results will result in a reduction in human error, which will ultimately benefit patient safety.”

Conventional endotoxin detection methods for parenteral pharmaceuticals are labour-intensive and error-prone, as they involve manual data entry and template set-up steps. As a consequence, the reliability of results can be compromised and the retest rate increased. At the same time, no metadata is associated with the manual steps, which limit traceability and the laboratory's audit capability.

“Less work for quicker and better results – that is our simple yet profound goal for our endotoxin testing customers,” said Robert Porzio, Product Manager for Endotoxin Detection at Lonza. “Our new solution reduces manual intervention considerably, minimizing the human error potential and the need for repeat test runs – all of which help enhance laboratory efficiencies. As a fully automated system, the PyroTec Pro solution captures preparation metadata, adding traceability into tracking, trending and audit controls.”

The new solution is being tested for ease-of-use in a trial carried out at Lonza’s Chemical and Microbial Manufacturing site in Visp (CH).

Dr. Jan Erik Rau, Head of the QC Microbiology Department at the site, explained: “The user will be able to operate the system without any programming or scripting knowledge. The robot automatically executes all processing required to complete an analytical run, while the WinKQC software v6.0 receives and saves the results and then transfers them into and out of laboratory information management systems or Lonza’s Moda solution.”

Restek's ever-growing selection of cannabis reference standards has expanded again with a new cannabigerolic acid (CBGA) CRM.

This certified reference material (CRM) is U.S. DEA exempt, so there's no need to purchase costly neat materials, make your own standards, or deal with DEA forms and registrations. Verified in composition and stability, this CBGA standard is ideal for combining with other Restek cannabinoid CRMs for quantitative potency analysis using the Raptor ARC-18 LC column.

And like all Restek certified reference materials (CRMs), it is manufactured and QC tested in ISO-accredited labs to satisfy ISO requirements.